Impediments to therapeutic advances for patients with gastroesophageal adenocarcinoma

Esophageal Endoprosthesis by Laparo- Gastroscopy with Transtumoral Drilling – Palliative Therapeutic Option in Advanced Gastroesophageal Junction Adenocarcinoma

Therapeutic approaches to gastroesophageal junction adenocarcinomas.

The following, from the 12th OESO World Conference: Cancers of the Esophagus, includes commentaries on the distinction between adenocarcinomas above, below, or within the gastroesophageal junction; combined modality therapy; tumor markers for use in personalized medicine; PET-CT and endoscopic biopsies in the evaluation of response to neoadjuvant chemoradiation therapy; a standardized grading s...

External beam radiation and high-dose-rate brachytherapy for elderly patients with gastroesophageal junction adenocarcinoma

PURPOSE The aim of this study was to retrospectively observe and analyze the long-term treatment outcomes of 96 elderly patients with gastroesophageal junction adenocarcinoma (GEJAC) who were treated with californium-252 (252Cf) neutron brachytherapy (NBT) in combination with external beam radiotherapy (EBRT) with or without chemotherapy. MATERIAL AND METHODS From January 2002 to November 201...

characteristics and survival rate of patients with gastric and gastroesophageal junction adenocarcinoma in yazd, iran

background: gastric cancer is the leading cause of cancer deaths in iran. treatment for gastric adenocarcinoma varies worldwide. the aim of this study is to evaluate char- acteristics and survival rate of gastric and gastroesophageal junction adenocarcinoma in yazd, iran. methods: this study was conducted on 53 patients with gastric or gastroesophageal junction adenocarcioma who referred to sha...

Prognostic Importance and Therapeutic Implications of PAK1, a Drugable Protein Kinase, in Gastroesophageal Junction Adenocarcinoma

Gastroesophageal junction (GEJ) adenocarcinoma is a lethal cancer with rising incidence, yet the molecular biomarkers that have strong prognostic impact and also hold great therapeutic promise remain elusive. We used a data mining approach and identified the p21 protein-activated kinase 1 (PAK1), an oncogene and drugable protein kinase, to be among the most promising targets for GEJ adenocarcin...